Electroconvulsive Therapy and the Longitudinal Modulation of Sleep Architecture
Our findings demonstrate that ECT increases N3 sleep and SWA in the responders' group, with SWA changes mediating improvements in depressive symptoms. These findings highlight SWA as a biomarker of antidepressant response and a potential target for sleep-based strategies to augment brain stimulation therapies for depression.
Authors
- Lucas Lebovitz
- Ben Julian A. Palanca (ORCID: https://orcid.org/0000-0001-7535-5701)
- Zitian Zhou (ORCID: https://orcid.org/0000-0001-9804-5159)
- Nuri B. Farber (ORCID: https://orcid.org/0000-0003-3178-1877)
- Alyssa K. Labonte (ORCID: https://orcid.org/0000-0001-9660-9280)
- Subha Subramanian
- Yo-El S Ju
- Mohammad Mehdi Kafashan
- Robby Greenspan
- CET-REM Study Team
- Nan Lin
Institutions
- Heart Rhythm Society (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- École Nationale Vétérinaire d'Alfort (FR)
- University of Washington (US)
- Washington University in St. Louis (US)
- ProQuest (United States) (US)
- Directorate-General for Interpretation (BE)
- Artistic Realization Technologies (US)
- Graduate School USA (US)
Publication Details
- Journal
- Journal of Ect
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1097/yct.0000000000001265
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00