Impact of switching high-sensitivity cardiac troponin assays on risk stratification in suspected acute coronary syndrome

Risk stratification thresholds for hs-cTnI and hs-cTnT assays do not provide equivalent performance. The hs-cTnT assay and threshold identified fewer low-risk patients suitable for discharge, with fewer subsequent cardiovascular events at 1 year.

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Publication Details

Journal
European Heart Journal Acute Cardiovascular Care
Published
2026-03-26
DOI
https://doi.org/10.1093/ehjacc/zuag042
Primary Topic
Acute Myocardial Infarction Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Impact of switching high-sensitivity cardiac troponin assays on risk stratification in suspected acute coronary syndrome

Sara Jenks, Deepak Harry, Paul Fineran, Rebecca Pattenden et al.
European Heart Journal Acute Cardiovascular Care
Acute Myocardial Infarction Research
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Impact of switching high-sensitivity cardiac troponin assays on risk stratification in suspected acute coronary syndrome

Sara Jenks, Deepak Harry, Paul Fineran, Rebecca Pattenden, A Gray, Ziwen Li, Jonathan Malo, Dimitrios Doudesis, M Mcdermott, C Tuck, N L M Cruden, Alexander J F Thurston, Kuan Ken Lee, Yong Yong Tew, Nicholas L Mills, Jasper Boeddinghaus, Atul Anand, Caelan Taggart, Anda Bularga, Ryan Wereski, Andrew R Chapman
article en

Abstract

Risk stratification thresholds for hs-cTnI and hs-cTnT assays do not provide equivalent performance. The hs-cTnT assay and threshold identified fewer low-risk patients suitable for discharge, with fewer subsequent cardiovascular events at 1 year.

European Heart Journal Acute Cardiovascular Care
University of Basel (CH), Western General Hospital (GB), Edinburgh Royal Infirmary (GB), Cardiovascular Institute Hospital (JP), University of Edinburgh (GB)
Openalex Percentile: Top 10%
Acute Myocardial Infarction Research
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