A practical advancement in FFL single-sided AM MPI: Achieving rabbit-scale 3D imaging without object movement in depth

For clinical applications, magnetic particle imaging (MPI) requires a large and open field of view (FOV) for flexible operation and interventional integration. Although an existing field-free-line (FFL) single-sided MPI provides high sensitivity, it typically relies on slow mechanical translation for 3D depth encoding. To overcome this limitation, we employ an amplitude modulation (AM) approach using decoupled drive and excitation coils, enabling pure electronic depth scanning up to 30 mm. The proposed rabbit-scale system achieves a 40 × 40 × 30 mm³ FOV and provides a practical solution for localized interventional applications such as sentinel lymph node biopsy.