Increases in total HIV-1 nucleic acid in whole blood precede plasma rna rebound during paediatric analytical treatment interruption

PoC HIV-1 TNA testing offers a more rapid and lower-volume method to detect viral rebound in paediatric ATI, enhancing safety monitoring and timely ART reinitiation.

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Publication Details

Journal
AIDS
Published
2026-03-26
DOI
https://doi.org/10.1097/qad.0000000000004506
Primary Topic
HIV Research and Treatment
Type
article
Field-Weighted Citation Impact
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article

Increases in total HIV-1 nucleic acid in whole blood precede plasma rna rebound during paediatric analytical treatment interruption

M. C. Puertas, Nicholas Herbert, Gabriela Cromhout, Kogielambal Chinniah et al.
AIDS
HIV Research and Treatment
article

Increases in total HIV-1 nucleic acid in whole blood precede plasma rna rebound during paediatric analytical treatment interruption

M. C. Puertas, Nicholas Herbert, Gabriela Cromhout, Kogielambal Chinniah, Jeroen van Lobenstein, Roopesh Bhoola, Nomonde Bengu, Rowena Fillis, Samantha Kannie, Malini Krishna, Philip JR Goulder, Javier Martinez-Picado, Moherndran Archary, Maria C. Garcia-Guerrero, Noxolo Mahlaba, Thumbi Ndung’u
article en

Abstract

PoC HIV-1 TNA testing offers a more rapid and lower-volume method to detect viral rebound in paediatric ATI, enhancing safety monitoring and timely ART reinitiation.

AIDS
Universitat de Vic - Universitat Central de Catalunya (ES), Institució Catalana de Recerca i Estudis Avançats (ES), Instituto de Salud Carlos III (ES), Ragon Institute of MGH, MIT and Harvard (US), University of Oxford (GB), IrsiCaixa (ES), Stanger Hospital (ZA), Queen Nandi Regional Hospital (ZA), Medawar Building for Pathogen Research (GB), Centro de Investigación Biomédica en Red (ES), Africa Health Research Institute (ZA), Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (ES), Mahatma Gandhi Memorial Hospital (ZA), University College London (GB), University of KwaZulu-Natal (ZA)
Good health and well-being
Openalex Percentile: Top 15%
HIV Research and Treatment
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Increases in total HIV-1 nucleic acid in whole blood precede plasma rna rebound during paediatric analytical treatment interruption — M. C. Puertas, Nicholas Herbert, et al. · AIDS (2026) | TGRS Research Map | TGRS