Dose–Response Association Between Handgrip Strength and All‐Cause Mortality Across Different Levels of Systemic Inflammation

Handgrip strength demonstrates a strong inverse dose-response association with mortality across varying inflammation levels. Protective effects persist even with elevated inflammatory markers, supporting handgrip strength as an accessible biomarker for mortality risk stratification in older adults regardless of inflammatory status.

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Publication Details

Journal
Journal of Cachexia Sarcopenia and Muscle
Published
2026-03-27
DOI
https://doi.org/10.1002/jcsm.70272
Primary Topic
Nutrition and Health in Aging
Type
article
Field-Weighted Citation Impact
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article

Dose–Response Association Between Handgrip Strength and All‐Cause Mortality Across Different Levels of Systemic Inflammation

Lars L. Andersen, Rodrigo Núñez‐Cortés, Carlos Cruz‐Montecinos, Ana Polo‐López et al.
Journal of Cachexia Sarcopenia and Muscle
Nutrition and Health in Aging
article

Dose–Response Association Between Handgrip Strength and All‐Cause Mortality Across Different Levels of Systemic Inflammation

Lars L. Andersen, Rodrigo Núñez‐Cortés, Carlos Cruz‐Montecinos, Ana Polo‐López, Joaquín Calatayud, Andrea Tur‐Boned, Rubén López‐Bueno, Luis Suso‐Martí
article en

Abstract

Handgrip strength demonstrates a strong inverse dose-response association with mortality across varying inflammation levels. Protective effects persist even with elevated inflammatory markers, supporting handgrip strength as an accessible biomarker for mortality risk stratification in older adults regardless of inflammatory status.

Journal of Cachexia Sarcopenia and MuscleVol. 17(2)
Universitat de València (ES), National Research Centre for the Working Environment (DK), University of Chile (CL), Universidad de Navarra (ES)
Good health and well-being
Openalex Percentile: Top 5%
Nutrition and Health in Aging
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