Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

We concluded that Prdx4 as a protective factor plays a critical role in preserving spermatogenesis by alleviating testicular OS and ferroptosis, and that Prdx4 may be known as a potential target in mitigating the adverse effects of natural aging and OS injury.

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Publication Details

Journal
Andrology
Published
2026-03-27
DOI
https://doi.org/10.1111/andr.70221
Primary Topic
Redox biology and oxidative stress
Type
article
Field-Weighted Citation Impact
0.00
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article

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

B. Zhang, Xiaoyu Yang, Shuning Yuan, Jiayin Liu et al.
Andrology
Redox biology and oxidative stress
article

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

B. Zhang, Xiaoyu Yang, Shuning Yuan, Jiayin Liu, Nini Wei, Chao Gao, Li Gao, Weiwei Ma, Yugui Cui, Mengting Hu, Yan Meng
article en

Abstract

We concluded that Prdx4 as a protective factor plays a critical role in preserving spermatogenesis by alleviating testicular OS and ferroptosis, and that Prdx4 may be known as a potential target in mitigating the adverse effects of natural aging and OS injury.

Andrology
Nantong University (CN), Nantong Maternity and Child Health Hospital (CN), Jiangsu Province Hospital (CN), Nanjing Medical University (CN)
Openalex Percentile: Top 6%
Redox biology and oxidative stress
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