Effect of pharmacokinetically-relevant ivermectin concentrations on survivorship and fecundity of Anopheles coluzzii and Aedes aegypti in Burkina Faso: A laboratory experimental study
IVM concentrations typically achieved in human plasma during MDA campaigns were sufficient to significantly reduce both survival and fecundity of wild type An. coluzzii, but had no measurable effect on Ae. aegypti. These findings highlight the species-specific response to IVM and support its potential role in integrated vector control strategies targeting malaria vectors in Africa.
Authors
- Sunil Parikh (ORCID: https://orcid.org/0000-0001-9411-5180)
- Brian D. Foy (ORCID: https://orcid.org/0000-0002-9117-203X)
- Romaric Ouedraogo
- André Barembaye Sagna (ORCID: https://orcid.org/0000-0001-8586-792X)
- Mady Ndiaye
- Elhadji Niang
- Greg Pugh (ORCID: https://orcid.org/0000-0002-2826-3131)
- Saoudatou Bagayogo
- Cheick Oumar W. Ouédraogo
- Fabrice A. Somé
- S. Rodrigue Dah
- Emmanuel Sougué
- Roch K. Dabiré
Institutions
- Centre de Coopération Internationale en Recherche Agronomique pour le Développement (FR)
- Université de Montpellier (FR)
- Yale University (US)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Centre de Recherche et de Veille sur les Maladies Emergentes dans l’Océan Indien (FR)
- Institut de Recherche en Sciences de la Santé (BF)
- Colorado State University (US)
- Cheikh Anta Diop University (SN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1371/journal.pone.0332677
- Primary Topic
- Parasitic Diseases Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00