The Association Between Multiple Myeloma and Neuropsychiatric Manifestations: A Narrative Review
The association between MM and neuropsychiatric manifestations is likely multifactorial. This review underscores the critical need for integrated mental health support within MM management and calls for further research into possible causes such as pathophysiological inflammation, paraneoplastic phenomena related to monoclonal proteins, and prolonged exposure to steroid therapy. Routine neuropsychiatric screening and assessment are imperative for timely identification and intervention to improve overall prognosis in MM patients.
Authors
- Laurel Spaccarelli
- Joanna Kowalik (ORCID: https://orcid.org/0000-0002-0060-4854)
- Srinagesh Mannekote Thippaiah (ORCID: https://orcid.org/0000-0002-9162-8105)
- M F Block
- Catherine S. Taghizadeh
- Natalie Ertz‐Archambault
Institutions
- Creighton University (US)
- Valley Medical Center (US)
- Healthwise (US)
Publication Details
- Journal
- Psycho-Oncology
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1002/pon.70438
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00