Insights From Matrix Metalloproteinase-2 Genotypes to Decipher the Genetic Architecture of Bladder Cancer Risk

<i>MMP-2</i> rs2285053 and, to a lesser extent, rs243865 polymorphisms may influence BLCA susceptibility and aggressiveness, particularly in the context of age and smoking. These variants may serve as potential biomarkers for personalized risk assessment, pending validation in larger, multiethnic cohorts.

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Publication Details

Journal
Anticancer Research
Published
2026-03-27
DOI
https://doi.org/10.21873/anticanres.18079
Primary Topic
Protease and Inhibitor Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Insights From Matrix Metalloproteinase-2 Genotypes to Decipher the Genetic Architecture of Bladder Cancer Risk

Shu-Yu Chang, HOU-YU SHIH, CHENG-HSI LIAO, CHAO-HSIANG CHANG et al.
Anticancer Research
Protease and Inhibitor Mechanisms
article

Insights From Matrix Metalloproteinase-2 Genotypes to Decipher the Genetic Architecture of Bladder Cancer Risk

Shu-Yu Chang, HOU-YU SHIH, CHENG-HSI LIAO, CHAO-HSIANG CHANG, YUN-CHI WANG, CHIA-WEN TSAI, WEN-CHI CHEN, WEN-SHIN CHANG, DA-TIAN BAU, JAW-CHYUN CHEN
article en

Abstract

<i>MMP-2</i> rs2285053 and, to a lesser extent, rs243865 polymorphisms may influence BLCA susceptibility and aggressiveness, particularly in the context of age and smoking. These variants may serve as potential biomarkers for personalized risk assessment, pending validation in larger, multiethnic cohorts.

Anticancer ResearchVol. 46(4)
Dayeh University (TW), Asia University (TW), China Medical University (TW), China Medical University Hospital (TW), Taichung Armed Forces General Hospital (TW), National Defense Medical Center (TW)
Good health and well-being
Openalex Percentile: Top 6%
Protease and Inhibitor Mechanisms
DOISourceOpenAlex
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