Efficacy, Safety, and Net Clinical Benefit of Post‐Atrial Fibrillation Ablation Anticoagulation

This meta-analysis suggests that after successful AF ablation, continuing OAC does not significantly reduce stroke risk compared to cessation or switching to aspirin, but it may increase major bleeding. While NCB trends favor cessation, the low absolute event rates and the risk of silent AF recurrence necessitate caution.

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Publication Details

Journal
Pacing and Clinical Electrophysiology
Published
2026-03-26
DOI
https://doi.org/10.1111/pace.70224
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy, Safety, and Net Clinical Benefit of Post‐Atrial Fibrillation Ablation Anticoagulation

Rana Rashwan, Azad Mojahedi, Mohamed Elnady, Mahmoud M. Shams et al.
Pacing and Clinical Electrophysiology
Atrial Fibrillation Management and Outcomes
article

Efficacy, Safety, and Net Clinical Benefit of Post‐Atrial Fibrillation Ablation Anticoagulation

Rana Rashwan, Azad Mojahedi, Mohamed Elnady, Mahmoud M. Shams, Ahmed Mohamed, Moshe Gunsburg, Imad Samman Tahhan, Zeyad Kholeif, A E Elalfy, Mustafa Abomohsen, Ahmed Farid Gadelmawla, Abdul Hakim Almakadma, Mohab Elnashar
article en

Abstract

This meta-analysis suggests that after successful AF ablation, continuing OAC does not significantly reduce stroke risk compared to cessation or switching to aspirin, but it may increase major bleeding. While NCB trends favor cessation, the low absolute event rates and the risk of silent AF recurrence necessitate caution.

Pacing and Clinical Electrophysiology
Lincoln Medical Center (US), Brigham and Women's Hospital (US), New York City Health and Hospitals Corporation (US), Kafrelsheikh University (EG), Harvard University (US), Wellington City Council (NZ), Jacksonville College (US), Brookdale University Hospital and Medical Center (US), Digestive CARE (US), Northeast Baptist Hospital (US), Mayo Clinic in Florida (US), Menoufia University (EG), University of Arkansas for Medical Sciences (US)
Openalex Percentile: Top 11%
Atrial Fibrillation Management and Outcomes
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Efficacy, Safety, and Net Clinical Benefit of Post‐Atrial Fibrillation Ablation Anticoagulation — Rana Rashwan, Azad Mojahedi, et al. · Pacing and Clinical Electrophysiology (2026) | TGRS Research Map | TGRS