Age-related genomic characterization and therapeutic targets in Chinese breast cancer: insights from prospective targeted sequencing and clinical data analysis

Our study, which makes use of the largest Chinese breast cancer sequencing cohort, sought to characterize the age-related genomic profile of breast cancer patients and identify novel therapeutic opportunities for individuals with breast cancer.

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Publication Details

Journal
BMC Medicine
Published
2026-03-27
DOI
https://doi.org/10.1186/s12916-026-04655-9
Primary Topic
Cancer Genomics and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
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article

Age-related genomic characterization and therapeutic targets in Chinese breast cancer: insights from prospective targeted sequencing and clinical data analysis

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BMC Medicine
Cancer Genomics and Diagnostics
article

Age-related genomic characterization and therapeutic targets in Chinese breast cancer: insights from prospective targeted sequencing and clinical data analysis

Xiao-Qing Song, Xin-Yi Sui, X. Hu, Chao Chen, Lei Fan, Zhi-Ming Shao, Xi-Yu Liu
article en

Abstract

Our study, which makes use of the largest Chinese breast cancer sequencing cohort, sought to characterize the age-related genomic profile of breast cancer patients and identify novel therapeutic opportunities for individuals with breast cancer.

BMC Medicine
Shanghai Medical College of Fudan University (CN), Sir Run Run Shaw Hospital (CN), Fudan University Shanghai Cancer Center (CN), Zhejiang University (CN)
Good health and well-being
Openalex Percentile: Top 6%
Cancer Genomics and Diagnostics
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