All-cause and cause-specific mortality in social anxiety disorder: a matched cohort and sibling cohort study

Individuals with SAD face an increased risk of mortality, attributable primarily to unnatural causes of death, such as suicide, but also to natural causes, even after adjusting for socioeconomic variables. Psychiatric comorbidities, particularly substance use disorders, and shared familial factors may also contribute to this excess death. Further study of underlying mechanisms may inform prevention and early intervention strategies to reduce mortality in this vulnerable population.

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Publication Details

Journal
Epidemiology and Psychiatric Sciences
Published
2026-01-01
DOI
https://doi.org/10.1017/s2045796026100535
Primary Topic
Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Type
article
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article

All-cause and cause-specific mortality in social anxiety disorder: a matched cohort and sibling cohort study

Henrik Larsson, Lorena Fernández de la Cruz, David Mataix-Cols, Anna Sidorchuk et al.
Epidemiology and Psychiatric Sciences
Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
article

All-cause and cause-specific mortality in social anxiety disorder: a matched cohort and sibling cohort study

Henrik Larsson, Lorena Fernández de la Cruz, David Mataix-Cols, Anna Sidorchuk, Josep Pol-Fuster, Kayoko Isomura, Ralf Kuja-Halkola, Brian D'Onofrio, Zheng Chang, Paul Lichtenstein
article en

Abstract

Individuals with SAD face an increased risk of mortality, attributable primarily to unnatural causes of death, such as suicide, but also to natural causes, even after adjusting for socioeconomic variables. Psychiatric comorbidities, particularly substance use disorders, and shared familial factors may also contribute to this excess death. Further study of underlying mechanisms may inform prevention and early intervention strategies to reduce mortality in this vulnerable population.

Epidemiology and Psychiatric SciencesVol. 35
Lund University (SE), Örebro University (SE), Karolinska Institutet (SE), Stockholm Health Care Services (SE), Indiana University (US)
Good health and well-being
Openalex Percentile: Top 10%
Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
DOIOpen Access PDFOpenAlex
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All-cause and cause-specific mortality in social anxiety disorder: a matched cohort and sibling cohort study — Henrik Larsson, Lorena Fernández de la Cruz, et al. · Epidemiology and Psychiatric Sciences (2026) | TGRS Research Map | TGRS