Baseline Urinary Calcium and the Efficacy of Thiazide Diuretics for Kidney Stone Prevention

Greater urine calcium reductions after thiazide treatment are observed among those with higher baseline urine calcium, and higher thiazide dose led to a larger reduction. These data are relevant for individualizing thiazide dose for kidney stone prevention.

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Publication Details

Journal
The Journal of Urology
Published
2026-03-27
DOI
https://doi.org/10.1097/ju.0000000000005042
Primary Topic
Kidney Stones and Urolithiasis Treatments
Type
article
Field-Weighted Citation Impact
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article

Baseline Urinary Calcium and the Efficacy of Thiazide Diuretics for Kidney Stone Prevention

John R. Asplin, Joseph J. Crivelli, Vahakn B. Shahinian, Phyllis Yan et al.
The Journal of Urology
Kidney Stones and Urolithiasis Treatments
article

Baseline Urinary Calcium and the Efficacy of Thiazide Diuretics for Kidney Stone Prevention

John R. Asplin, Joseph J. Crivelli, Vahakn B. Shahinian, Phyllis Yan, Sarah Best, Ryan S. Hsi, Pietro Manuel Ferraro, Gary C. Curhan, John M. Hollingsworth
article en

Abstract

Greater urine calcium reductions after thiazide treatment are observed among those with higher baseline urine calcium, and higher thiazide dose led to a larger reduction. These data are relevant for individualizing thiazide dose for kidney stone prevention.

The Journal of Urology
University of Verona (IT), Brigham and Women's Hospital (US), University of Wisconsin–Madison (US), University of California, Irvine (US), University of Michigan (US), University of Alabama at Birmingham (US), University of Florida (US), Link Foundation (US), Vanderbilt University Medical Center (US), Florida College (US)
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Openalex Percentile: Top 5%
Kidney Stones and Urolithiasis Treatments
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Baseline Urinary Calcium and the Efficacy of Thiazide Diuretics for Kidney Stone Prevention — John R. Asplin, Joseph J. Crivelli, et al. · The Journal of Urology (2026) | TGRS Research Map | TGRS