Metabolomic Profile of Genetic Liability to Type 2 Diabetes Among 125,000 Mexican Adults: A Mendelian Randomization Study
T2D is associated with widespread changes in the circulating metabolome among adults in Mexico, reflecting diverse biological mechanisms and highlighting the importance of effective T2D management, including control of T2D-associated dyslipidemia, in this population.
Authors
- Alejandra Vergara (ORCID: https://orcid.org/0009-0004-7036-144X)
- P. Kuri-Morales
- Tabitha Hubbard (ORCID: https://orcid.org/0009-0008-0689-710X)
- Raúl Ramírez-Reyes (ORCID: https://orcid.org/0000-0001-9763-324X)
- William Guy Herrington (ORCID: https://orcid.org/0000-0003-1172-8243)
- Rachel Wade (ORCID: https://orcid.org/0000-0001-9826-6322)
- Paulina Baca
- Roberto Tapia-Conyer
- Louisa Gnatiuc Friedrichs
- Jaime Berumen
- Eirini Trichia
- Adrián Garcilazo-Ávila
- Jesus Alegre-Diaz
- Jonathan R. Emberson
- Diego Aguilar-Ramirez
- Richard Peto
- Fernando Rivas
- Michael Hill
- Jason M. Torres
- Carlos González-Carballo
- Fiona Bragg
- Rory Collins
Institutions
- University of Oxford (GB)
- Science Oxford (GB)
- Universidad Nacional Autónoma de México (MX)
- Tecnológico de Monterrey (MX)
Publication Details
- Journal
- Diabetes Care
- Published
- 2026-03-27
- DOI
- https://doi.org/10.2337/dc25-2933
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00