The causal impact of older siblings’ academic achievement on younger siblings’ risk for drug use disorder: instrumental variable and propensity score analyses

Findings from two causal inference approaches support a largely causal link between low AA in an older sibling and increased DUD risk in younger siblings. Stronger effects in close-aged and male-male pairs further support this conclusion. Interventions to improve AA in older siblings may yield indirect preventive benefits for younger siblings.

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Publication Details

Journal
Psychological Medicine
Published
2026-01-01
DOI
https://doi.org/10.1017/s0033291726103729
Primary Topic
Advanced Causal Inference Techniques
Type
article
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article

The causal impact of older siblings’ academic achievement on younger siblings’ risk for drug use disorder: instrumental variable and propensity score analyses

Abigail A. Fagan, K S Kendler, Henrik Ohlsson, Kristina Sundquist et al.
Psychological Medicine
Advanced Causal Inference Techniques
article

The causal impact of older siblings’ academic achievement on younger siblings’ risk for drug use disorder: instrumental variable and propensity score analyses

Abigail A. Fagan, K S Kendler, Henrik Ohlsson, Kristina Sundquist, Jan Sundquist
article en

Abstract

Findings from two causal inference approaches support a largely causal link between low AA in an older sibling and increased DUD risk in younger siblings. Stronger effects in close-aged and male-male pairs further support this conclusion. Interventions to improve AA in older siblings may yield indirect preventive benefits for younger siblings.

Psychological MedicineVol. 56
Virginia Commonwealth University (US), Lund University (SE), University of Florida (US), Primary Health Care (QA), Skåne University Hospital (SE)
Good health and well-being
Openalex Percentile: Top 11%
Advanced Causal Inference Techniques
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The causal impact of older siblings’ academic achievement on younger siblings’ risk for drug use disorder: instrumental variable and propensity score analyses — Abigail A. Fagan, K S Kendler, et al. · Psychological Medicine (2026) | TGRS Research Map | TGRS