Impact Assessment of the Allergy Fact Checker, a Clinical Decision Support Tool for Noninvasive Beta-Lactam Antibiotic Allergy Label Delabeling: Protocol for a Multicenter Crossover Cluster-Controlled Study

This is the first multicenter European study evaluating a strictly noninvasive BLAL delabeling approach. If successful, this AFC tool could improve antimicrobial stewardship, reduce costs, and provide a scalable model for centralized allergy label management.

Authors

Rik Schrijvers (ORCID: https://orcid.org/0000-0002-4261-6220)
Greet Van De Sijpe (ORCID: https://orcid.org/0000-0003-1475-6178)
Liesbeth Gilissen (ORCID: https://orcid.org/0000-0003-0927-3104)
Isabel Spriet (ORCID: https://orcid.org/0000-0001-6342-0676)

Institutions

KU Leuven (BE)

Publication Details

Journal: JMIR Research Protocols
Published: 2026-03-27
DOI: https://doi.org/10.2196/86056
Primary Topic: Drug-Induced Adverse Reactions
Type: article
Field-Weighted Citation Impact: 0.00

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article

Impact Assessment of the Allergy Fact Checker, a Clinical Decision Support Tool for Noninvasive Beta-Lactam Antibiotic Allergy Label Delabeling: Protocol for a Multicenter Crossover Cluster-Controlled Study

Rik Schrijvers, Greet Van De Sijpe, Liesbeth Gilissen, Isabel Spriet

Mar 27, 2026

JMIR Research Protocols

Drug-Induced Adverse Reactions

article

Impact Assessment of the Allergy Fact Checker, a Clinical Decision Support Tool for Noninvasive Beta-Lactam Antibiotic Allergy Label Delabeling: Protocol for a Multicenter Crossover Cluster-Controlled Study

Rik Schrijvers, Greet Van De Sijpe, Liesbeth Gilissen, Isabel Spriet

March 27, 2026article en

Abstract

This is the first multicenter European study evaluating a strictly noninvasive BLAL delabeling approach. If successful, this AFC tool could improve antimicrobial stewardship, reduce costs, and provide a scalable model for centralized allergy label management.

JMIR Research ProtocolsVol. 15

KU Leuven (BE)

Peace, Justice and strong institutions

Openalex Percentile: Top 5%

Drug-Induced Adverse Reactions

DOI Open Access PDF OpenAlex

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