High-flux hemodialysis combined with nutritional intervention: Effects on the nutritional status and clinical outcomes of patients with renal failure

High-flux-based hemodialysis prescription with nutritional support was associated with more effective clearance of uremic markers, improvements in nutritional status and inflammatory response, as well as better survival in renal failure patients. Elevated IL-6 and TNF-α levels were identified as significant predictors of mortality in the reduced Cox model.

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Publication Details

Journal
PLoS ONE
Published
2026-03-27
DOI
https://doi.org/10.1371/journal.pone.0345943
Primary Topic
Dialysis and Renal Disease Management
Type
article
Field-Weighted Citation Impact
0.00
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article

High-flux hemodialysis combined with nutritional intervention: Effects on the nutritional status and clinical outcomes of patients with renal failure

Xuehua Pu, Binbin Zhang, Rongrong Shen, Yang Liu et al.
PLoS ONE
Dialysis and Renal Disease Management
article

High-flux hemodialysis combined with nutritional intervention: Effects on the nutritional status and clinical outcomes of patients with renal failure

Xuehua Pu, Binbin Zhang, Rongrong Shen, Yang Liu, Yaqing Zhou
article en

Abstract

High-flux-based hemodialysis prescription with nutritional support was associated with more effective clearance of uremic markers, improvements in nutritional status and inflammatory response, as well as better survival in renal failure patients. Elevated IL-6 and TNF-α levels were identified as significant predictors of mortality in the reduced Cox model.

PLoS ONEVol. 21(3)
Nanjing University of Chinese Medicine (CN), Nantong University (CN), Affiliated Hospital of Nantong University (CN), Second People's Hospital of NanTong (CN), The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN), Yancheng Third People's Hospital (CN), Nanjing Medical University (CN)
Zero hunger
Openalex Percentile: Top 5%
Dialysis and Renal Disease Management
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High-flux hemodialysis combined with nutritional intervention: Effects on the nutritional status and clinical outcomes of patients with renal failure — Xuehua Pu, Binbin Zhang, et al. · PLoS ONE (2026) | TGRS Research Map | TGRS