Macrophage β-catenin-Ihh axis induces hepatic stellate cell activation and fibrosis in metabolic dysfunction-associated steatohepatitis
Our findings identify the macrophage β-catenin-Ihh axis as a key regulator for controlling hepatic steatosis and fibrosis during MASH.
Authors
- Zhongya Xu
- R. Zhang (ORCID: https://orcid.org/0000-0002-7678-8813)
- Yelin Yang (ORCID: https://orcid.org/0000-0001-6118-8973)
- YunXia Chai
- Feng Xiao
- Mingzheng Chen
- Wenjie Sun
- Qiang Zhu
- Yifei He
- Jiajing Qiu
Institutions
- Second Military Medical University (CN)
- Nanjing Children's Hospital (CN)
- Changhai Hospital (CN)
- Eastern Hepatobiliary Surgery Hospital (CN)
- Wuxi People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Inflammation Research
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1007/s00011-026-02220-x
- Primary Topic
- Liver physiology and pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00