Pd-Catalyzed Regioselective Hydrocarboxylation of Olefins Solely Using Formic Acid without Activator
A wide variety of linear carboxylic acids bearing various functional groups can be efficiently obtained in up to 99% yield, with >20:1 l/b ratios from a wide range of terminal or internal olefins via hydrocarboxylation with formic acid (HCO<sub>2</sub>H) using Pd(OAc)<sub>2</sub> and 1,2-DTBPMB as catalyst under mild conditions. The reaction is performed in a relatively simple manner without the need for any additional activator or strong acid promoter.
Authors
- Yu Fu (ORCID: https://orcid.org/0000-0003-3025-7766)
- Fengyin Wang
- J. Jenny Li (ORCID: https://orcid.org/0009-0003-0597-0970)
- Yahui Zhuang
- Tianci Shen
- Tao Zhu
- Yian Shi
Institutions
- Catalytic Materials (United States) (US)
- Changzhou University (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1021/acs.joc.5c02878
- Primary Topic
- Carbon dioxide utilization in catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00