Prospective untreated outcomes in patients with cerebral cavernous malformation
Most patients improved after a first hemorrhage, with the most improvement occurring in year 1. Disability increased with each SH. Disability was associated with 2 or more SHs, a brainstem location, and a self-reported psychiatric diagnosis. Ten-year disability risk with a nonbrainstem CCM location was < 8%.
Authors
- Kelly D. Flemming (ORCID: https://orcid.org/0000-0001-6021-1190)
- Giuseppe Lanzino
- Delal Bektas
- Robert D. Brown
Institutions
- Mayo Clinic (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Journal of neurosurgery
- Published
- 2026-03-01
- DOI
- https://doi.org/10.3171/2025.11.jns251526
- Primary Topic
- Vascular Malformations Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00