JI-CJ001 Enhances Paclitaxel Sensitivity in Gastric Cancer Cell Lines through Inhibition of HER2/mTOR Signaling and Induction of Autophagy

Collectively, these findings indicate that JI-CJ001 enhances the therapeutic impact of PTX in gastric cancer cell lines through regulation of HER2/mTOR signaling and autophagy. These results highlight JI-CJ001 as a promising natural adjuvant for improving the efficacy of conventional chemotherapy in gastric cancer.

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Publication Details

Journal
Anticancer Research
Published
2026-03-27
DOI
https://doi.org/10.21873/anticanres.18089
Primary Topic
Autophagy in Disease and Therapy
Type
article
Field-Weighted Citation Impact
0.00
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article

JI-CJ001 Enhances Paclitaxel Sensitivity in Gastric Cancer Cell Lines through Inhibition of HER2/mTOR Signaling and Induction of Autophagy

S R Lee, Chunhoo Cheon, MIN-WOO KIM, SEONG-GYU KO et al.
Anticancer Research
Autophagy in Disease and Therapy
article

JI-CJ001 Enhances Paclitaxel Sensitivity in Gastric Cancer Cell Lines through Inhibition of HER2/mTOR Signaling and Induction of Autophagy

S R Lee, Chunhoo Cheon, MIN-WOO KIM, SEONG-GYU KO, SO EUN PARK
article en

Abstract

Collectively, these findings indicate that JI-CJ001 enhances the therapeutic impact of PTX in gastric cancer cell lines through regulation of HER2/mTOR signaling and autophagy. These results highlight JI-CJ001 as a promising natural adjuvant for improving the efficacy of conventional chemotherapy in gastric cancer.

Anticancer ResearchVol. 46(4)
Kyung Hee Cyber University (KR), Kyung Hee University (KR)
Good health and well-being
Openalex Percentile: Top 7%
Autophagy in Disease and Therapy
DOISourceOpenAlex
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