STING pathway contributes to Steroid-Hyporesponsive Lung Inflammation in DSS-induced colitis mice model
The significant activation of the STING pathway and dysregulation of steroid signature markers in the lungs of DSS-induced colitis mice suggest a novel mechanism by which gut inflammation may propagate to the lungs.
Authors
- Bushra Mdkhana (ORCID: https://orcid.org/0000-0003-0938-2239)
- Ibrahim Y. Hachim (ORCID: https://orcid.org/0000-0001-6438-9455)
- Balachandar Selvakumar (ORCID: https://orcid.org/0000-0002-9568-2731)
- Shirin Ali
- Baraa Khalid Salah Al-Sheakly
- Narjes Saheb Sharif-Askari
- Nival Ali
- Fatemeh Saheb Sharif-Askari
- Rabih Halwani
- Mariam Wed Eladham
Institutions
- Alfaisal University (SA)
- King Saud University (SA)
- University of Sharjah (AE)
- Fahd bin Sultan University (SA)
- University of Tabuk (SA)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1371/journal.pone.0344511
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00