On the relationships between apathy, depression and anhedonia
Apathy, depression and anhedonia are dissociable constructs with distinct symptom signatures. Emotional apathy is a unique dimension which provides a novel target for research. A 10-item Apathy-Depression-Anhedonia Measure developed here provides a pragmatic tool for rapid, precise phenotyping to guide more personalised therapeutic strategies.
Authors
- Kübra Fethiye Karataş (ORCID: https://orcid.org/0009-0001-4776-2227)
- Y. Ang
- Sijia Zhao (ORCID: https://orcid.org/0000-0002-6246-0702)
- Sanjay Manohar (ORCID: https://orcid.org/0000-0003-0735-4349)
- Jacqueline Scholl (ORCID: https://orcid.org/0000-0001-9969-1355)
- Matthew A J Apps (ORCID: https://orcid.org/0000-0001-5793-2202)
- M. Husain
- C. Harmer
- Kan He (ORCID: https://orcid.org/0000-0002-0125-8383)
- Kai You Wang (ORCID: https://orcid.org/0000-0002-6170-4744)
- A. K. Sen
- P. L. Lockwood
- Qianqian Li
- Rong Ye
- Simon J Little
- Meijia Li
Institutions
- Birmingham City University (GB)
- University of California, San Francisco (US)
- Anhui Medical University (CN)
- John Radcliffe Hospital (GB)
- Institute of High Performance Computing (SG)
- University College Birmingham (GB)
- University of Oxford (GB)
- Centre de Recherche en Neurosciences de Lyon (FR)
- Anhui Provincial Hospital (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
- Anhui Mental Health Center (CN)
- University of Birmingham (GB)
Publication Details
- Journal
- Journal of Neurology Neurosurgery & Psychiatry
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1136/jnnp-2025-337245
- Primary Topic
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00