Diuretic Resistance Risk and the Efficacy of Natriuresis-Guided Diuretic Therapy in Acute Heart Failure
Patients with a high BAN-ADHF score had impaired natriuresis and worse clinical outcomes. Natriuresis-guided therapy improved 24-hour natriuresis consistently across the spectrum of BAN-ADHF scores, with enhanced natriuretic effects at later time points among those with high DR risk. (Pragmatic Urinary Sodium AlgoritHm in Acute Heart Failure [PUSH-AF]; NCT04606927).
Authors
- Iris E. Beldhuis (ORCID: https://orcid.org/0000-0002-3679-168X)
- Wybe Nieuwland (ORCID: https://orcid.org/0000-0003-2829-3127)
- Lara E.E.C. Zonneveld
- Ambarish Pandey
- Joan C. Trullas
- Jozine M. ter Maaten
- Peter van der Meer
- Jenifer E. Coster
- Dirk J. van Veldhuisen
- Kevin Damman
- Adriaan A. Voors
Institutions
- Universitat de Vic - Universitat Central de Catalunya (ES)
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- JACC Heart Failure
- Published
- 2026-03-01
- DOI
- https://doi.org/10.1016/j.jchf.2026.103017
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00