Global economic differences in modern glioblastoma care – a systematic review

The cost of modern GBM treatment varies greatly between the analyzed countries with adjuvant treatment and inpatient care being the most important cost drivers in western countries in the direct medical costs analyses. Cost models show that the Stupp protocol remains a significant financial burden in resource-limited settings, underlining the cost-effectiveness of surgery in modern GBM management. There is, however, a need for uniform cost reporting to correctly assess cost-effectiveness across global healthcare systems.