The Glucose and Glutamine Requirements of Cancer and Normal Cells Do Not Distinguish Them, in Contrast to Their Methionine Requirement, Suggesting the Warburg Effect Is Not a Cancer Paradigm

The Warburg effect of glucose and glutamine addiction is not cancer specific in comparison to methionine addiction (Hoffman effect), which is cancer specific, suggesting the Warburg effect is not a cancer paradigm.

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Publication Details

Journal
Anticancer Research
Published
2026-03-27
DOI
https://doi.org/10.21873/anticanres.18080
Primary Topic
Cancer Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

The Glucose and Glutamine Requirements of Cancer and Normal Cells Do Not Distinguish Them, in Contrast to Their Methionine Requirement, Suggesting the Warburg Effect Is Not a Cancer Paradigm

Yasunori Tome, KOHEI MIZUTA, Tomoyuki Ishiguro, Byung Mo Kang et al.
Anticancer Research
Cancer Research and Treatments
article

The Glucose and Glutamine Requirements of Cancer and Normal Cells Do Not Distinguish Them, in Contrast to Their Methionine Requirement, Suggesting the Warburg Effect Is Not a Cancer Paradigm

Yasunori Tome, KOHEI MIZUTA, Tomoyuki Ishiguro, Byung Mo Kang, YUTA MIYASHI, JIN SOO KIM, KOTARO NISHIDA, ROBERT M. HOFFMAN, QINGHONG HAN, SHUKUAN LI, MICHAEL BOUVET
article en

Abstract

The Warburg effect of glucose and glutamine addiction is not cancer specific in comparison to methionine addiction (Hoffman effect), which is cancer specific, suggesting the Warburg effect is not a cancer paradigm.

Anticancer ResearchVol. 46(4)
University of the Ryukyus (JP), University of California San Diego (US), AntiCancer (United States) (US)
Openalex Percentile: Top 5%
Cancer Research and Treatments
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