ABO-Incompatible Platelet Transfusions and Mortality Risk in Patients With Intracranial Hemorrhage

Acute platelet transfusion practice remains prevalent in ICH, and platelet transfusion-related 30-day mortality risk may be influenced by ABO-incompatible platelet units. Clinical trials are needed to assess whether transfusion practice changes in providing ABO-matched platelets can improve outcomes in certain patients with ICH.

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Publication Details

Journal
Neurosurgery
Published
2026-03-27
DOI
https://doi.org/10.1227/neu.0000000000004006
Primary Topic
Blood transfusion and management
Type
article
Field-Weighted Citation Impact
0.00
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article

ABO-Incompatible Platelet Transfusions and Mortality Risk in Patients With Intracranial Hemorrhage

Matthew S. Karafin, Melissa M. Cushing, Jonathan M. Davis, Deborah B. Bookwalter et al.
Neurosurgery
Blood transfusion and management
article

ABO-Incompatible Platelet Transfusions and Mortality Risk in Patients With Intracranial Hemorrhage

Matthew S. Karafin, Melissa M. Cushing, Jonathan M. Davis, Deborah B. Bookwalter, Travis Lee, Jerome L. Gottschall, Grant Sinson, Elizabeth F. Stone, Ritchard G. Cable, Eldad A. Hod, David Roh, Claude Hemphill, S. H. Kleinman, Bryan Spencer, Emily J. Gilmore, Patrick Mitchell, Alan E. Mast
article en

Abstract

Acute platelet transfusion practice remains prevalent in ICH, and platelet transfusion-related 30-day mortality risk may be influenced by ABO-incompatible platelet units. Clinical trials are needed to assess whether transfusion practice changes in providing ABO-matched platelets can improve outcomes in certain patients with ICH.

Neurosurgery
University of North Carolina at Chapel Hill (US), Froedtert Hospital (US), Yale New Haven Hospital (US), Westat (United States) (US), American Red Cross (US), University of British Columbia (CA), University of California, San Francisco (US), Cornell University (US), Versiti Blood Center of Wisconsin (US), Columbia University (US)
Good health and well-being
Openalex Percentile: Top 7%
Blood transfusion and management
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