Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer
These findings will allow clinicians to proactively conduct stricter monitoring of patients at higher risk for L-asparaginase-induced pancreatitis and inform future development of protective agents that can be used concomitantly to mitigate their risk.
Authors
- Kerry B. Goralski
- Edward J. Raack (ORCID: https://orcid.org/0000-0001-9730-9415)
- Geoff D.E. Cuvelier (ORCID: https://orcid.org/0000-0003-4493-8757)
- Michelle Higginson
- Erika N. Scott (ORCID: https://orcid.org/0000-0003-4660-7206)
- Miguel Córdova‐Delgado (ORCID: https://orcid.org/0000-0002-3132-226X)
- Gabriella Groeneweg
- Maja Krajinović (ORCID: https://orcid.org/0000-0003-4772-7031)
- Denis Lebel (ORCID: https://orcid.org/0000-0001-8431-1700)
- K. C. Li
- Bruce Carleton (ORCID: https://orcid.org/0000-0002-4485-4054)
- Lucie Pecheux
- Fudan Miao
- Awatif M. Abuzgaia
- Derek Yau (ORCID: https://orcid.org/0000-0001-8113-7962)
- Donna L. Johnston (ORCID: https://orcid.org/0000-0001-6145-9809)
- Zara Forbrigger (ORCID: https://orcid.org/0000-0003-2090-3138)
- Ketan Prasad Kulkarni (ORCID: https://orcid.org/0000-0002-6758-2290)
- Jessica N. Trueman
- Shahrad R. Rassekh (ORCID: https://orcid.org/0000-0001-8005-2641)
- Catrina M. Loucks (ORCID: https://orcid.org/0000-0003-1167-3721)
- Michael Rieder (ORCID: https://orcid.org/0000-0003-3079-2873)
- Paul Nathan (ORCID: https://orcid.org/0000-0002-2327-3250)
- Spencer J. Anderson (ORCID: https://orcid.org/0000-0002-2969-8399)
- Michelle Staub
- W.S.C. Chang
- H. Ghimire
- Kathleen Felton
- Gesche Riabowol
- Thai Hoa Tran
- Gregory Guilcher
- Jean‐François Bussières
- Bina Gyawali
- Sara Khalaj
- Colin J. D. Ross
- Mounira Ibrahim
- Jessica Tewfik
- Tamorah Lewis
- Thaïna‐Rafi Jean‐Baptiste
- Geert ’t Jong
Institutions
- University of British Columbia (CA)
- Children's Hospital of Eastern Ontario (CA)
- Izaak Walton Killam Health Centre (CA)
- London Health Sciences Centre (CA)
- Hospital for Sick Children (CA)
- Alberta Children's Hospital (CA)
- Centre Hospitalier Universitaire Sainte-Justine (CA)
- Health Sciences Centre (CA)
- BC Children's Hospital (CA)
- Stollery Children's Hospital (CA)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1002/1545-5017.70284
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.00