Real-world patterns of maintenance therapy after allogeneic transplant in older adults with acute myeloid leukemia: A Medicare cohort study
In this first real-world analysis of post-alloHCT FLT3-TKI maintenance in older adults, utilization was low and adherence was modest, although not impaired by age alone. Gilteritinib demonstrated the highest adherence and appeared to have favorable tolerability. Strategies to improve adherence and prospective data in older adults are needed to maximize the benefits of FLT3-TKI maintenance in this population.
Authors
- Alana Block
- David Nimke (ORCID: https://orcid.org/0000-0002-3938-3366)
- Priti Pednekar (ORCID: https://orcid.org/0000-0002-0543-6677)
- Peter Kardel
- Vanessa E. Kennedy
- Christopher Young
Institutions
- Palo Alto University (US)
- District of Columbia Department of Health (US)
- Stanford Medicine (US)
- Astellas Pharma (United States) (US)
- Stanford University (US)
Publication Details
- Journal
- Journal of Geriatric Oncology
- Published
- 2026-03-27
- DOI
- https://doi.org/10.1016/j.jgo.2026.102959
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00