Subcorneal Pustular Dermatosis (Sneddon-Wilkinson Disease): A Case Report of a Chronic Pustular Rash in a 10-year-old Boy

Abstract Subcorneal pustular dermatosis (SPD) is a rare neutrophilic condition characterized as a chronic and relapsing pustular skin eruption that usually affects the trunk in adults. Rare cases have been reported in the pediatric population. We report a 10-year-old boy who presented with recurrent pustular eruptions on his face, trunk, and extremities. Clinico-pathological correlation confirmed the diagnosis of SPD, and he was successfully treated with acitretin. This report highlights a less common presentation of SPD in a pediatric patient and reinforces the fact that SPD remains an important differential that should be considered in all patients who present with chronic and relapsing pustular lesions.

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Publication Details

Journal
Indian Journal of Paediatric Dermatology
Published
2026-01-01
DOI
https://doi.org/10.4103/ijpd.ijpd_71_25
Primary Topic
Autoimmune and Inflammatory Disorders
Type
article
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article

Subcorneal Pustular Dermatosis (Sneddon-Wilkinson Disease): A Case Report of a Chronic Pustular Rash in a 10-year-old Boy

Emily Yiping Gan, Mark Jean Aan Koh, Jin Ho Chong, Fatima Jacinto-Calimag
Indian Journal of Paediatric Dermatology
Autoimmune and Inflammatory Disorders
article

Subcorneal Pustular Dermatosis (Sneddon-Wilkinson Disease): A Case Report of a Chronic Pustular Rash in a 10-year-old Boy

Emily Yiping Gan, Mark Jean Aan Koh, Jin Ho Chong, Fatima Jacinto-Calimag
article en

Abstract

Abstract Subcorneal pustular dermatosis (SPD) is a rare neutrophilic condition characterized as a chronic and relapsing pustular skin eruption that usually affects the trunk in adults. Rare cases have been reported in the pediatric population. We report a 10-year-old boy who presented with recurrent pustular eruptions on his face, trunk, and extremities. Clinico-pathological correlation confirmed the diagnosis of SPD, and he was successfully treated with acitretin. This report highlights a less common presentation of SPD in a pediatric patient and reinforces the fact that SPD remains an important differential that should be considered in all patients who present with chronic and relapsing pustular lesions.

Indian Journal of Paediatric DermatologyVol. 27(1)
KK Women's and Children's Hospital (SG), National Eczema Association (US)
Good health and well-being
Openalex Percentile: Top 8%
Autoimmune and Inflammatory Disorders
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Subcorneal Pustular Dermatosis (Sneddon-Wilkinson Disease): A Case Report of a Chronic Pustular Rash in a 10-year-old Boy — Emily Yiping Gan, Mark Jean Aan Koh, et al. · Indian Journal of Paediatric Dermatology (2026) | TGRS Research Map | TGRS