Radiographic Progression With and Without Prostate-Specific Antigen Rise in Patients With Advanced Prostate Cancer Treated With Enzalutamide

Given the frequent discordance and poor prognosis of imaging-based progression in the absence of PSA changes during enzalutamide treatment in mHSPC and nmCRPC, periodic surveillance using imaging is recommended.

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Publication Details

Journal
Journal of Clinical Oncology
Published
2026-03-27
DOI
https://doi.org/10.1200/jco-24-02829
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Radiographic Progression With and Without Prostate-Specific Antigen Rise in Patients With Advanced Prostate Cancer Treated With Enzalutamide

M. Hussain, David G. Russell, Gabriel P. Haas, Taro Iguchi et al.
Journal of Clinical Oncology
Prostate Cancer Treatment and Research
article

Radiographic Progression With and Without Prostate-Specific Antigen Rise in Patients With Advanced Prostate Cancer Treated With Enzalutamide

M. Hussain, David G. Russell, Gabriel P. Haas, Taro Iguchi, Matt Rosales, Nicolas Mottet, Cora N. Sternberg, Arun A. Azad, Fred Saad, Arnulf Stenzl, Andrew J. Armstrong
article en

Abstract

Given the frequent discordance and poor prognosis of imaging-based progression in the absence of PSA changes during enzalutamide treatment in mHSPC and nmCRPC, periodic surveillance using imaging is recommended.

Journal of Clinical Oncology
Northwestern University (US), Kanazawa Medical University (JP), The University of Melbourne (AU), Pfizer (United States) (US), Cornell University (US), Peter MacCallum Cancer Centre (AU), Duke Medical Center (US), Centre Hospitalier Universitaire de Saint-Étienne (FR), Astellas Pharma (United States) (US), Weill Cornell Medicine (US), Université de Montréal (CA), University of Tübingen (DE)
Openalex Percentile: Top 6%
Prostate Cancer Treatment and Research
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Radiographic Progression With and Without Prostate-Specific Antigen Rise in Patients With Advanced Prostate Cancer Treated With Enzalutamide — M. Hussain, David G. Russell, et al. · Journal of Clinical Oncology (2026) | TGRS Research Map | TGRS