Patient Image-Based Hemodynamics of Intracranial Aneurysms: An In Silico Study

The aim of this research was to calculate hemodynamics of intracaranial aneurysms using computational fluid dynamics. The hemodynamics research of intracranial aneurysms used patient-specific blood pressure data and anonymised DICOM images, from which aneurysm geometries were extracted. The following boundary conditions were established. At the inlet, a pulsatile velocity profile was enforced, and a pressure waveform was assigned at the outlet. Numerical simulations were performed to examine key hemodynamic parameters linked to aneurysm rupture, including wall shear stress, time-averaged wall shear stress, oscillatory shear index, and relative residence time, as well as flow distributions. On the basis of these hemodynamic indicators, the risk of rupture was connected with a geometric property of the aneurysm, the aspect ratio. The hemodynamics parameters obtained ranges with the results of other scientific studies. Finally, it was concluded that combining clinical data, aneurysm geometry, and hemodynamic characteristics can provide clinicians with valuable additional information to use in selection of the appropriate treatment strategy for intracranial aneurysms.