Safety and Efficacy of the VASCADE MVP® XL Venous Vascular Closure System for Management of Femoral Venotomy Following Catheter‐Based Interventions Utilizing 16‐17F OD Sheaths: The AMBULATE EXPAND Trial

The study results demonstrate that the VASCADE MVP XL device provides safe and effective percutaneous closure of femoral venous access sites after catheter-based procedures using 16-17F OD sheaths. Compared to standard performance goals from manual compression, the VASCADE MVP XL significantly reduced time to ambulation, hemostasis, discharge eligibility, and overall post-procedure time.

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Publication Details

Journal
Journal of Cardiovascular Electrophysiology
Published
2026-03-27
DOI
https://doi.org/10.1111/jce.70324
Primary Topic
Vascular Procedures and Complications
Type
article
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article

Safety and Efficacy of the VASCADE MVP® XL Venous Vascular Closure System for Management of Femoral Venotomy Following Catheter‐Based Interventions Utilizing 16‐17F OD Sheaths: The AMBULATE EXPAND Trial

S. Mittal, Maheer Gandhavadi, Joseph Banno, Bruce G. Hook et al.
Journal of Cardiovascular Electrophysiology
Vascular Procedures and Complications
article

Safety and Efficacy of the VASCADE MVP® XL Venous Vascular Closure System for Management of Femoral Venotomy Following Catheter‐Based Interventions Utilizing 16‐17F OD Sheaths: The AMBULATE EXPAND Trial

S. Mittal, Maheer Gandhavadi, Joseph Banno, Bruce G. Hook, Zayd Eldadah, David B. De Lurgio, H. Thomas McElderry, Amin Al‐Ahmad, T. Jared Bunch
article en

Abstract

The study results demonstrate that the VASCADE MVP XL device provides safe and effective percutaneous closure of femoral venous access sites after catheter-based procedures using 16-17F OD sheaths. Compared to standard performance goals from manual compression, the VASCADE MVP XL significantly reduced time to ambulation, hemostasis, discharge eligibility, and overall post-procedure time.

Journal of Cardiovascular Electrophysiology
Emory Healthcare (US), Overlake Hospital Medical Center (US), University of Utah Hospital (US), University of Alabama at Birmingham (US), Valley Health System (US), Lahey Medical Center (US), St David's Medical Center (US), Texas Cardiac Arrhythmia (US), MedStar Heart & Vascular Institute (US)
Good health and well-being
Openalex Percentile: Top 6%
Vascular Procedures and Complications
DOISourceOpenAlex
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Safety and Efficacy of the VASCADE MVP® XL Venous Vascular Closure System for Management of Femoral Venotomy Following Catheter‐Based Interventions Utilizing 16‐17F OD Sheaths: The AMBULATE EXPAND Trial — S. Mittal, Maheer Gandhavadi, et al. · Journal of Cardiovascular Electrophysiology (2026) | TGRS Research Map | TGRS