SRS136 - A comparative study of wire-guided <i>versus</i> pintuation-guided wide local excision in breast cancer surgery

Abstract Background Accurate localisation is essential in breast-conserving surgery to ensure oncological safety while maintaining cosmesis. Wire-guided localisation (WGL) has long been the standard, though it presents limitations including patient discomfort and logistical challenges. This study compares surgical outcomes between WGL and a novel pintuation-guided excision technique in breast cancer patients undergoing wide local excision. Methods A retrospective cohort study was conducted involving 100 patients with early-stage breast cancer undergoing breast-conserving surgery between [June 2024-July 2025]. Fifty patients underwent wire-guided localisation, while fifty underwent pintuation-guided excision, a technique involving pre-operative localisation . Data collected included margin status, re-excision rates, operative time, and patient-reported outcomes. Results Pintuation-guided excision demonstrated superior outcomes in several key areas:Clear margin rates were significantly higher in the pintuation group (94%) compared to the wire-guided group (82%) (P &amp;lt; 0.05).Re-excision rates were lower in the pintuation group (6 versus 18%).Operative time was reduced by an average of 12 min in the pintuation group.Patient-reported satisfaction with the localisation process was higher in the pintuation group. No significant difference was observed in post-operative complications or pathology findings between the two groups. Conclusions Pintuation-guided excision appears to be a safe and effective alternative to wire-guided localisation in breast-conserving surgery, offering improved margin clearance, reduced re-excision rates, and better patient experience. Further prospective studies are warranted to validate these findings and assess long-term outcomes.