Favorable association between early initiation of sodium-glucose cotransporter-2 inhibitors and in-hospital prognosis in acute myocardial infarction

Together with traditional medical treatment, initiating SGLT2i within 24 hours of admission for acute myocardial infarction was independently associated with lower in-hospital mortality. These findings suggest a potential association between early SGLT2i use and improved in-hospital outcomes and warrant further investigation in prospective randomized studies.

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Publication Details

Journal
PLoS ONE
Published
2026-03-27
DOI
https://doi.org/10.1371/journal.pone.0345315
Primary Topic
Diabetes Treatment and Management
Type
article
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article

Favorable association between early initiation of sodium-glucose cotransporter-2 inhibitors and in-hospital prognosis in acute myocardial infarction

Bao Quoc Dinh, AnLe Pham, Tuan Minh Nguyen, Si Van Nguyen et al.
PLoS ONE
Diabetes Treatment and Management
article

Favorable association between early initiation of sodium-glucose cotransporter-2 inhibitors and in-hospital prognosis in acute myocardial infarction

Bao Quoc Dinh, AnLe Pham, Tuan Minh Nguyen, Si Van Nguyen, Anh Thi Kim Nguyen, Hung Thanh Quach, Tuan Ngoc Tran, Tien Dung Ho, Hoang Huy Bui
article en

Abstract

Together with traditional medical treatment, initiating SGLT2i within 24 hours of admission for acute myocardial infarction was independently associated with lower in-hospital mortality. These findings suggest a potential association between early SGLT2i use and improved in-hospital outcomes and warrant further investigation in prospective randomized studies.

PLoS ONEVol. 21(3)
University of Medicine and Pharmacy at Ho Chi Minh City (VN), HCMC Hospital of Dermato Venereology (VN)
No poverty
Openalex Percentile: Top 7%
Diabetes Treatment and Management
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