Trigger-Negative Takotsubo Syndrome ― A Distinct Phenotype Prone to Recurrence ―

assessments, longer follow-up, and evaluations will be required to validate and further refine these findings. ConclusionsThis study provides important insights the recurrence of TTS and highlights the heterogeneity of this disorder.The of trigger-negative TTS as a phenotype prone to recurrence supports a shift from a stress-only paradigm toward a more nuanced, phenotype-oriented understanding of the syndrome.Although many questions remain unanswered, this study represents a meaningful step toward improving individual risk stratification and the long-term management of patients with TTS.

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Publication Details

Journal
Circulation Reports
Published
2026-03-27
DOI
https://doi.org/10.1253/circrep.cr-26-0033
Primary Topic
Takotsubo Cardiomyopathy and Associated Phenomena
Type
article
Field-Weighted Citation Impact
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article

Trigger-Negative Takotsubo Syndrome ― A Distinct Phenotype Prone to Recurrence ―

Kazuna Hayashi, H. Toda, Kazufumi Nakamura
Circulation Reports
Takotsubo Cardiomyopathy and Associated Phenomena
article

Trigger-Negative Takotsubo Syndrome ― A Distinct Phenotype Prone to Recurrence ―

Kazuna Hayashi, H. Toda, Kazufumi Nakamura
article en

Abstract

assessments, longer follow-up, and evaluations will be required to validate and further refine these findings. ConclusionsThis study provides important insights the recurrence of TTS and highlights the heterogeneity of this disorder.The of trigger-negative TTS as a phenotype prone to recurrence supports a shift from a stress-only paradigm toward a more nuanced, phenotype-oriented understanding of the syndrome.Although many questions remain unanswered, this study represents a meaningful step toward improving individual risk stratification and the long-term management of patients with TTS.

Circulation Reports
Okayama University (JP), Okayama University Hospital (JP)
Openalex Percentile: Top 16%
Takotsubo Cardiomyopathy and Associated Phenomena
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