Automatic alveolar ventilation-targeted NIV mode vs polysomnographic titration of fixed pressure in naive patients with chronic respiratory failure

This study shows that iVAPS AE initiated with the 'learned target' procedure achieved similar short and long-term ventilatory efficacy to PSG manual bilevel titration. However, its higher pressure levels and lower comfort indicate that the modes are not fully equivalent. Moreover, underestimation of the AHI by the built-in software demands careful interpretation before changing ventilatory settings. Further studies are required to determine the long-term clinical relevance of these differences.

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Publication Details

Journal
SLEEP
Published
2026-03-26
DOI
https://doi.org/10.1093/sleep/zsag085
Primary Topic
Respiratory Support and Mechanisms
Type
article
Field-Weighted Citation Impact
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article

Automatic alveolar ventilation-targeted NIV mode vs polysomnographic titration of fixed pressure in naive patients with chronic respiratory failure

M Dalmases, A. Gálvez Moraleda, Mónica Matute-Villacís, Cristina Embid et al.
SLEEP
Respiratory Support and Mechanisms
article

Automatic alveolar ventilation-targeted NIV mode vs polysomnographic titration of fixed pressure in naive patients with chronic respiratory failure

M Dalmases, A. Gálvez Moraleda, Mónica Matute-Villacís, Cristina Embid, Leticia Escuredo, Marta Puig Dupré, Àlvar Agustí, Gemma Guerrero Romero, Dunia Gascueña
article en

Abstract

This study shows that iVAPS AE initiated with the 'learned target' procedure achieved similar short and long-term ventilatory efficacy to PSG manual bilevel titration. However, its higher pressure levels and lower comfort indicate that the modes are not fully equivalent. Moreover, underestimation of the AHI by the built-in software demands careful interpretation before changing ventilatory settings. Further studies are required to determine the long-term clinical relevance of these differences.

SLEEP
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES), Hospital Clínic de Barcelona (ES), Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (ES), Hospital Universitari Germans Trias i Pujol (ES), Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES), Universitat de Barcelona (ES)
Openalex Percentile: Top 6%
Respiratory Support and Mechanisms
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