Investigation of the Relationship Between Prodynorphin Gene Polymorphisms and Sensory Differences in Children With Autism Spectrum Disorder

Due to the preliminary nature of this investigation and the relatively small sample size, these findings should be interpreted with caution and require validation in larger cohorts. These preliminary findings suggest a potential modulatory role of PDYN gene variants in sensory processing characteristics among children with ASD. These novel findings warrant replication in larger cohorts to validate the influence of PDYN polymorphisms on sensory phenotypes and to further clarify their neurobiological relevance.

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Publication Details

Journal
International Journal of Developmental Neuroscience
Published
2026-03-26
DOI
https://doi.org/10.1002/jdn.70118
Primary Topic
Neuropeptides and Animal Physiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Investigation of the Relationship Between Prodynorphin Gene Polymorphisms and Sensory Differences in Children With Autism Spectrum Disorder

Necla Şahin, Tuba Edgünlü, Ayşegül Demirtaş Bi̇lgi̇ç, Özge Dombaycı et al.
International Journal of Developmental Neuroscience
Neuropeptides and Animal Physiology
article

Investigation of the Relationship Between Prodynorphin Gene Polymorphisms and Sensory Differences in Children With Autism Spectrum Disorder

Necla Şahin, Tuba Edgünlü, Ayşegül Demirtaş Bi̇lgi̇ç, Özge Dombaycı, Gülsüm Demirkan Başkaya, Özlem Nehir Yazıcı, Hatice Topal
article en

Abstract

Due to the preliminary nature of this investigation and the relatively small sample size, these findings should be interpreted with caution and require validation in larger cohorts. These preliminary findings suggest a potential modulatory role of PDYN gene variants in sensory processing characteristics among children with ASD. These novel findings warrant replication in larger cohorts to validate the influence of PDYN polymorphisms on sensory phenotypes and to further clarify their neurobiological relevance.

International Journal of Developmental NeuroscienceVol. 86(2)
Manisa Celal Bayar University (TR), Muğla University (TR)
Openalex Percentile: Top 7%
Neuropeptides and Animal Physiology
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