Dock & Design: Engineering specificity for alternative pimaradiene outcome with the ent-kaurene synthase from Bradyrhizobium japonicum
The complexity of the reactions catalyzed by terpene synthases has hindered enzymatic engineering. In most cases such efforts result in non-specific product outcome, with the targeted compound being produced alongside...
Authors
- Reuben J. Peters (ORCID: https://orcid.org/0000-0003-4691-8477)
- Samuel Tufts
- Justin B. Siegel (ORCID: https://orcid.org/0000-0003-1782-4076)
- Dean J. Tantillo (ORCID: https://orcid.org/0000-0002-2992-8844)
- Qiang Wang
- Yue H. Zhang
- Meirong Jia
- Liang Jin
- Mark Schmidt-Dannert
Publication Details
- Journal
- Chemical Science
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1039/d5sc09199c
- Primary Topic
- Plant biochemistry and biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00