Acute limb ischemia in a morbidly obese diabetic patient with obstructive sleep apnea

Obstructive sleep apnea (OSA) is a common disorder with well-established cardiovascular associations, yet its link to acute limb ischemia (ALI) is rarely described. We report the case of a man in his 50s with morbid obesity having a history of OSA and diabetes mellitus who presented with sudden right leg pain, numbness, and pallor. Clinical evaluation and imaging confirmed ALI, prompting urgent transfemoral embolectomy under general anesthesia, which successfully restored limb perfusion. Laboratory workup revealed elevated hemoglobin (18 g/dL), and his history of chronic intermittent hypoxia suggested a prothrombotic milieu associated with untreated OSA. This case highlights ALI as a potential, although uncommon, thrombotic complication of OSA and underscores the importance of early recognition and intervention in high-risk patients.

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Publication Details

Journal
Medicine India
Published
2026-03-26
DOI
https://doi.org/10.25259/medindia_40_2025
Primary Topic
Obstructive Sleep Apnea Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Acute limb ischemia in a morbidly obese diabetic patient with obstructive sleep apnea

A. K. Sharma, Suraj Pai, Suresh Pai
Medicine India
Obstructive Sleep Apnea Research
article

Acute limb ischemia in a morbidly obese diabetic patient with obstructive sleep apnea

A. K. Sharma, Suraj Pai, Suresh Pai
article en

Abstract

Obstructive sleep apnea (OSA) is a common disorder with well-established cardiovascular associations, yet its link to acute limb ischemia (ALI) is rarely described. We report the case of a man in his 50s with morbid obesity having a history of OSA and diabetes mellitus who presented with sudden right leg pain, numbness, and pallor. Clinical evaluation and imaging confirmed ALI, prompting urgent transfemoral embolectomy under general anesthesia, which successfully restored limb perfusion. Laboratory workup revealed elevated hemoglobin (18 g/dL), and his history of chronic intermittent hypoxia suggested a prothrombotic milieu associated with untreated OSA. This case highlights ALI as a potential, although uncommon, thrombotic complication of OSA and underscores the importance of early recognition and intervention in high-risk patients.

Medicine IndiaVol. 0
Manipal Academy of Higher Education (IN)
Good health and well-being
Openalex Percentile: Top 6%
Obstructive Sleep Apnea Research
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