Investigating the Influence of Tranexamic Acid on Adipocyte Differentiation in an In Vitro Model
Clinically relevant concentrations of TXA do not impair adipose progenitor cell viability, proliferation, adipogenic differentiation, or thermogenic responsiveness in vitro. These findings support the cellular safety of TXA use in liposuction and fat grafting and provide reassurance as adoption of TXA continues to expand in plastic and reconstructive surgery.
Authors
- Silvia Corvera (ORCID: https://orcid.org/0000-0002-0009-4129)
- Giorgianna E. Ellis
- Tiffany DeSouza (ORCID: https://orcid.org/0000-0001-6237-1139)
- Alex Joo
- Janice F. Lalikos
- Jahnavi Challagonda
- Sneha Palmieri
- Anam J. Furrukh
Institutions
- University of Massachusetts Chan Medical School (US)
Publication Details
- Journal
- Annals of Plastic Surgery
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1097/sap.0000000000004702
- Primary Topic
- Body Contouring and Surgery
- Type
- article
- Field-Weighted Citation Impact
- 0.00