Eslicarbazepine Use During Breastfeeding: A Case Report

Although no previous data on the use of eslicarbazepine acetate during lactation are available, limited but reassuring data have been reported with oxcarbazepine, of which eslicarbazepine is a major metabolite. Given the well-known benefits of breastfeeding, and according to the above reassuring data, breastfeeding under clinical supervision could be considered for healthy full-term infants of mothers on eslicarbazepine acetate monotherapy. However, parents should be warned that data concerning the safety of eslicarbazepine during breastfeeding are scarce, and long-term neurodevelopment outcomes in breastfed children are unknown. Additionally, the infants' serum levels should be measured in case of an unexplained adverse reaction.

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Publication Details

Journal
Journal of Human Lactation
Published
2026-03-26
DOI
https://doi.org/10.1177/08903344261426739
Primary Topic
Maternal Mental Health During Pregnancy and Postpartum
Type
article
Field-Weighted Citation Impact
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article

Eslicarbazepine Use During Breastfeeding: A Case Report

Vial Thierry, Auffret Marine, Reversat-Brulant Thais, Pizzoglio-Billaudaz Véronique et al.
Journal of Human Lactation
Maternal Mental Health During Pregnancy and Postpartum
article

Eslicarbazepine Use During Breastfeeding: A Case Report

Vial Thierry, Auffret Marine, Reversat-Brulant Thais, Pizzoglio-Billaudaz Véronique, Bertin Blandine, Atzenhoffer Marina, Moschetti Sophie
article en

Abstract

Although no previous data on the use of eslicarbazepine acetate during lactation are available, limited but reassuring data have been reported with oxcarbazepine, of which eslicarbazepine is a major metabolite. Given the well-known benefits of breastfeeding, and according to the above reassuring data, breastfeeding under clinical supervision could be considered for healthy full-term infants of mothers on eslicarbazepine acetate monotherapy. However, parents should be warned that data concerning the safety of eslicarbazepine during breastfeeding are scarce, and long-term neurodevelopment outcomes in breastfed children are unknown. Additionally, the infants' serum levels should be measured in case of an unexplained adverse reaction.

Journal of Human Lactation
Université Claude Bernard Lyon 1 (FR), Hospices Civils de Lyon (FR), Laboratoire de Biométrie et Biologie Evolutive (FR)
Good health and well-being
Openalex Percentile: Top 9%
Maternal Mental Health During Pregnancy and Postpartum
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