Efficacy and feasibility of treating adults with paediatric chemotherapy protocols in Ewing sarcoma, rhabdomyosarcoma and osteosarcoma – a systematic review by the Australia and New Zealand Sarcoma Association clinical practice guidelines working par

The treatment of adults with EWS, RMS, and OSS remains an area of unmet need. Adequate chemotherapy exposure and inclusion of disease-specific therapeutic agents may be important elements in the optimal treatment of adults. Referral to a sarcoma reference centre is strongly recommended.

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Publication Details

Journal
Critical Reviews in Oncology/Hematology
Published
2026-03-01
DOI
https://doi.org/10.1016/j.critrevonc.2026.105301
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and feasibility of treating adults with paediatric chemotherapy protocols in Ewing sarcoma, rhabdomyosarcoma and osteosarcoma – a systematic review by the Australia and New Zealand Sarcoma Association clinical practice guidelines working par

Smaro Lazarakis, Julie Cayrol, Joanna Connor, Peter Grimison et al.
Critical Reviews in Oncology/Hematology
Sarcoma Diagnosis and Treatment
article

Efficacy and feasibility of treating adults with paediatric chemotherapy protocols in Ewing sarcoma, rhabdomyosarcoma and osteosarcoma – a systematic review by the Australia and New Zealand Sarcoma Association clinical practice guidelines working par

Smaro Lazarakis, Julie Cayrol, Joanna Connor, Peter Grimison, Natacha Omer, Jeremy Howard Lewin, Vivek A. Bhadri, Betty Y.H. Zhang, Mark Winstanley, Claire Carkeet, Deborah Di-Xin Zhou, Jean-Luc Vrisakis, Marianne B Phillips, Jasmine Mar, Angela M Hong
article en

Abstract

The treatment of adults with EWS, RMS, and OSS remains an area of unmet need. Adequate chemotherapy exposure and inclusion of disease-specific therapeutic agents may be important elements in the optimal treatment of adults. Referral to a sarcoma reference centre is strongly recommended.

Critical Reviews in Oncology/Hematology
The Royal Melbourne Hospital (AU), Royal Children's Hospital (AU), The Kids Research Institute Australia (AU), Royal Prince Alfred Hospital (AU), Gold Coast Hospital (AU), Peter MacCallum Cancer Centre (AU), Auckland City Hospital (NZ), Children’s Health Queensland Hospital and Health Service (AU), Chris O’Brien Lifehouse (AU), Starship Children's Health (NZ), Gold Coast Health (AU), Australia and New Zealand Sarcoma Association
Openalex Percentile: Top 7%
Sarcoma Diagnosis and Treatment
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Efficacy and feasibility of treating adults with paediatric chemotherapy protocols in Ewing sarcoma, rhabdomyosarcoma and osteosarcoma – a systematic review by the Australia and New Zealand Sarcoma Association clinical practice guidelines working par — Smaro Lazarakis, Julie Cayrol, et al. · Critical Reviews in Oncology/Hematology (2026) | TGRS Research Map | TGRS