Prevalence and risk factors of distant metastasis among Chinese osteosarcoma patients: a systematic review and meta-analysis

This and previous studies demonstrate that DM in OS is influenced by multiple known risk factors, most of which can be identified during preoperative assessment. The crucial step lies in translating these preoperative insights into concrete postoperative preventive actions. This approach holds significant value for improving clinical management quality and formulating individualized postoperative follow-up and intervention plans. These findings, derived from clinical data within a Chinese population, are particularly applicable to the management of OS patients in China, offering tailored guidance for this demographic.