Systematic Review and Meta-Analysis on Rescue Stenting for Large-Vessel Occlusion due to Underlying Intracranial Atherosclerotic Stenosis (ICAS)

In large-vessel occlusion due to intracranial atherosclerotic stenosis, rescue stenting is associated with higher reperfusion rates and improved 90-day functional outcomes without a statistically significant increase in symptomatic haemorrhage, while any mortality benefit remains uncertain. The certainty of the evidence is low, and randomized data are needed to confirm causality and optimize patient selection.