Baseline Cerebral Small Vessel Disease Predicting Long‐Term Cognitive Decline in Transient Ischemic Attack Patients

CSVD imaging markers are present in over half of TIA patients and are independently associated with cognitive decline up to 3 years, with the strongest effect on memory. Whether the presence of CMBs is the strongest predictive imaging biomarker of cognitive decline in TIA patients requires confirmation in further studies.

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Publication Details

Journal
European Journal of Neurology
Published
2026-03-26
DOI
https://doi.org/10.1111/ene.70578
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
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article

Baseline Cerebral Small Vessel Disease Predicting Long‐Term Cognitive Decline in Transient Ischemic Attack Patients

Matthias Endres, Ana Sofía Ríos, Thomas Ihl, Anna Kufner et al.
European Journal of Neurology
Dementia and Cognitive Impairment Research
article

Baseline Cerebral Small Vessel Disease Predicting Long‐Term Cognitive Decline in Transient Ischemic Attack Patients

Matthias Endres, Ana Sofía Ríos, Thomas Ihl, Anna Kufner, Pimrapat Gebert, Ahmed A. Khalil, Kersten Villringer, Uchralt Temuulen, Huma Fatima Ali, P. Roesen, M. Ahmadi, Ulrike Grittner, Heinrich J. Audebert, Charlotte Cordonnier, Laurent Puy, Tim Bastian Braemswig, Ramanan Ganeshan
article en

Abstract

CSVD imaging markers are present in over half of TIA patients and are independently associated with cognitive decline up to 3 years, with the strongest effect on memory. Whether the presence of CMBs is the strongest predictive imaging biomarker of cognitive decline in TIA patients requires confirmation in further studies.

European Journal of NeurologyVol. 33(4)
Inserm (FR), Université de Lille (FR), German Center for Neurodegenerative Diseases (DE), Centre Hospitalier Universitaire de Lille (FR), Humboldt-Universität zu Berlin (DE), German Centre for Cardiovascular Research (DE), Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE), Einstein Center for Neurosciences Berlin (DE), Charité - Universitätsmedizin Berlin (DE)
Good health and well-being
Openalex Percentile: Top 17%
Dementia and Cognitive Impairment Research
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