Clinical Validation of Digital PCR for Precise m.3243A>G Heteroplasmy Quantification in Early‐Onset Diabetes
The developed method can provide an accurate, reliable, rapid, simple, and low-cost evaluation of the heteroplasmy rate of m.3243A>G for both peripheral blood and urinary sediment. Thus, it is highly promising as a genetic screening method for early-onset diabetes related to m.3243A>G.
Authors
- Yongtong Cao (ORCID: https://orcid.org/0000-0002-2019-7088)
- Meimei Zhao
- Guoxiong Deng
- Hao Wang (ORCID: https://orcid.org/0009-0003-3042-4015)
- Xiaomu Kong
- Haoyan Zhu
- Lixia Lu
- Lei Bei
- Mo Li
- Yongwei Jiang
- Liang Ma
- Peng Gao
- Yi Liu
- Ziyi Feng
Institutions
- Target (United States) (US)
- China-Japan Friendship Hospital (CN)
Publication Details
- Journal
- Journal of Diabetes Research
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1155/jdr/9298888
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00