Traumatic Occlusion Exacerbates Bone Resorption by Modifying Gene Expression in the Bone Tissue of Ligature‐Induced Periodontitis in Mice
Traumatic occlusion accelerates bone resorption in ligature-induced periodontitis but does not independently cause significant bone loss. Occlusal trauma enhances the expression of inflammation-related genes, especially in bone with periodontitis.
Authors
- Tomomitsu Hirota
- Yujin Ohsugi (ORCID: https://orcid.org/0000-0002-2843-173X)
- Peiya Lin
- Yuta Tsukahara
- Takanori Iwata (ORCID: https://orcid.org/0000-0002-5461-7298)
- Yosuke Tsuchiya (ORCID: https://orcid.org/0000-0002-7592-7068)
- Yohei Hayashi
- Sayaka Katagiri
Institutions
- Jikei University School of Medicine (JP)
- Tokyo Medical and Dental University (JP)
- Joslin Diabetes Center (US)
- The Health Care Science Institute (JP)
Publication Details
- Journal
- Journal Of Clinical Periodontology
- Published
- 2026-03-26
- DOI
- https://doi.org/10.1111/jcpe.70112
- Primary Topic
- Dental Trauma and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00