Analysis of the Mediating Effect of Vitamin D via the TGF‐β1/Treg Pathway in the Pathogenesis of Childhood Primary Immune Thrombocytopenia
There is dysregulation of VitD, TGF-β1, and Treg cells in newly diagnosed children with ITP. TGF-β1 may be a key mediator of the regulation of ITP by VitD, suggesting the potential value of TGF- β1 as an intervening target.
Authors
- Shujun Li (ORCID: https://orcid.org/0009-0000-9153-5323)
- Dongju Zhao (ORCID: https://orcid.org/0000-0002-0589-5670)
- Bao Liu (ORCID: https://orcid.org/0000-0001-6359-959X)
- Jia Guo (ORCID: https://orcid.org/0000-0001-6733-8952)
- Rui Fan
- Peiling Li
- Yanyan Ma
- Zhihang Wang
- Mengru Chen
- Zhiyin Wang
Institutions
- First Affiliated Hospital of Xinxiang Medical University (CN)
Publication Details
- Journal
- Journal of Immunology Research
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1155/jimr/4001873
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00