Expression of PD-1/PD-L1 pathway molecules in human cardiac allograft according to acute cellular rejection status: insights from a Korean Heart Transplant Cohort
The PD-1/PD-L1 pathway is involved in ACR regulation in human cardiac allografts. Increased PD-L1 expression during ACR may represent a counteractive mechanism to limit alloimmune-mediated tissue injury, supporting PD-1/PD-L1 as a potential therapeutic target in heart TPL recipients.
Authors
- Jeemin Yim (ORCID: https://orcid.org/0000-0002-8571-7486)
- J. Koh
- Yoon Kyung Jeon
- Doo Hyun Chung
Institutions
- Seoul National University (KR)
- Seoul Metropolitan Government (KR)
- Seoul National University Hospital (KR)
- SNUH SMG-SNU Boramae Medical Center (KR)
Publication Details
- Journal
- Journal of Pathology and Translational Medicine
- Published
- 2026-03-27
- DOI
- https://doi.org/10.4132/jptm.2026.01.02
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00